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Omtrent seven-9 % af den kaukasiske befolkning har variationer i CYP2D6 genet som koder for ingen- eller nedsat aktivitet af CYP2D6 (se personlig medicin ). Tramadol et produg der omdannes til den aktive metabolit through CYP2D6. Patienter med nedsat eller manglende aktivitet af CYP2D6, vil have reduceret- eller manglende effekt af tramadol.Adult m

Bubblers are common because they mimic the working experience of smoking out of a bong but with far more compact hardware. Cannabis shoppers like bubblers because the water from the chamber will help cool down smoke to forestall throat discomfort.Thanks for looking at our Neighborhood guidelines. Please study the full list of publishing guidelines